F.B. Taylor, C.H. Toh, W.K. Hoots, H. Wada, M. Levi, On behalf of the Scientific Subcommitteee on Disseminated Intravascular Coagulation (DIC) of the. Abstract. ARANGO BARRIENTOS, Marcos. Disseminated intravascular coagulation. Iatreia [online]. , vol, n.4, pp ISSN La coagulación intravascular diseminada, o DIC por sus siglas en inglés, es una interrupción seria en el mecanismo de coagulación del cuerpo. Normalmente.

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High-dose antithrombin III in severe sepsis: The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

Age-related differences in outcome and severity of DIC in children with septic shock and purpura.

J Biol Chem ; Diagnosis and intravascualr of disseminated intravascular coagulation: How to cite this article. A simple scoring system has been proposed to aid in the diagnosis of this entity.

Coagulación Intravascular Diseminada

Membrane-dependent reactions in blood coagulation: Disseminated intravascular coagulation ; Hemorrhage ; Sepsis ; Thrombosis. Services on Inravascular Article. Treatment includes the specific management of the underlying cause that triggered the DIC, support with blood products in patients with bleeding manifestations and therapeutic anticoagulation in patients with thrombotic events.


Disseminated intravascular coagulation DIC is a frequent clinical entity that presents as a secondary phenomenon associated with some diseases, including, among others, severe infections, neoplastic disorders and obstetric catastrophes.

Antigua enfermedad, nueva esperanza 11 FEB In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant.

Significant correlations between tissue factor and thrombin markers in trauma and septic patients with disseminated intravascular coagulation. Use of protein C concentrate, heparin and haemofiltration in meningococcus-induced purpura fulminans. Spanish pdf Article in xml format Article references How to cite this article Automatic translation Send this article by e-mail.

The development of DIC is an adverse prognostic factor that significantly increases mortality. Genetic influence on cytokine production in meningococcal disease. Biochim Biophys Acta ; Dysfunction of endothelial protein C activation in severe meningococcal sepsis.

Disseminated intravascular coagulation is a frequent complication of systemic inflammatory response syndrome.

Nuevos aspectos sobre la coagulación intravascular diseminada – Artículos – IntraMed

Towards definition, clinical and laboratory criteria and a scoring system for disseminated intravascular coagulation. J Clin Invest ; It is characterized by a diffuse and simultaneous activation of the clotting and fibrinolytic systems. Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis.


In this review article the following aspects of CID are included: Gaz Med Paris ;2: Arch Pathol Lab Med ; A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation.

All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Distribution patterns of microthrombi in disseminated intravascular coagulation. Thrombin signalling and protease activated receptors.

Efficacy and safety of recombinant human activated protein C for severe sepsis. Activation of coagulation after administration of tumour necrosis factor to normal subjects. Monocyte vesiculation is a possible mechanism for dissemination of membrane associated procoagulant activities and adhesion molecules after stimulation with lipopolysaccharide.

Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. J Thromb Haemost ;1: