Apidra SoloStar Units/ml solution for injection in a pre-filled pen – Patient The Patient Information Leaflet (PIL) is the leaflet included in the pack with a. Apidra SoloStar Units/ml solution for injection in a pre-filled pen . SoloStar, the Instructions for use included in the Package leaflet must be read carefully. APIDRA [insulin glulisine injection (rDNA origin)] is a recombinant . package insert, and the pump manufacturer’s manual (see DOSAGE AND.

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Moderate Because cisapride can enhance gastric emptying in patients with diabetes, blood glucose can be affected, which, in turn, may affect the clinical response to insulin and other antidiabetic agents.

It is unclear if hemoglobin A1C is improved or if improvements are sustained with continued treatment beyond 24 weeks. Careful observation of increased maternal caloric needs and maternal blood glucose concentrations are needed. Monitor patients for increase in triglyceride concentrations. This pen is only for your use.

Insulin glulisine that has been exposed to temperatures greater than 37 degrees C Patients at aapidra include those with compromised renal function, those fasting for prolonged periods, those that are malnourished, and those receiving high or excessive doses of sulfonamides. Do not use insulin glulisine that inxert been frozen. Moderate Estramustine may decrease glucose tolerance leading to hyperglycemia.

Ask your pharmacist how to throw away medicines you no longer use. Push them out with the plunger and withdraw the correct dose.

Diabetes mellitus type 1 is caused by insulin deficiency ihsert diabetes mellitus type 2 is caused by a combination of insulin deficiency and resistance.

The pen in use must not be stored in a refrigerator. Patients should be closely monitored for changes in glycemic control while receiving propoxyphene in combination with antidiabetic agents. Another possible mechanism is impairment of beta-cell function.


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For information on the treatment of hypoglycaemia, see box at the end of this leaflet. Biosynthetic insulin is used as replacement therapy in patients with diabetes mellitus to temporarily restore their ability to use fats, carbohydrates, and proteins, and to convert glycogen to fat. Maintenance Protect your SoloStar from dust and dirt. Changes in insulin products like insulin glulisine should be made by experienced medical personnel.

It is advisable to test your blood sugar immediately after taking glucose to check that you really have hypoglycaemia.

Clean the rubber stopper of the vial with an alcohol wipe. Pasireotide inhibits the secretion of insulin and glucagon. Second, tobacco smoking is known to aggravate insulin resistance. Animal data indicate that MAOIs may stimulate insulin secretion. Insulin reacts antagonistically towards glucagon.

This medicine has been prescribed for you only. Speak to a doctor immediately if you are not able to control the hypoglycaemia or if it recurs. Moderate Monitor patients receiving pentoxifylline concomitantly with insulin for changes in glycemic control.

Aggravation of diabetes mellitus has been reported. Clean the rubber stopper of both vials of insulin with an alcohol wipe.

Initially, for each insulin dose, approximately one-third is given as a rapid-acting insulin and the other two-thirds is an intermediate-acting insulin. Choline Salicylate; Magnesium Salicylate: In each case, it may be necessary to adjust your insulin dose to avoid blood sugar levels that are either too low or too high.

Fever, thyroid disease, infection, recent trauma or surgery, diarrhea secondary to malabsorption, vomiting, and certain medications can also affect insulin requirements, requiring dosage adjustments.

Corticosteroids stimulate hepatic glucose production and inhibit peripheral glucose uptake into muscle and fatty tissues, producing insulin resistance. Apixra beta-blockers, such as atenolol or metoprolol, do not appear to potentiate insulin-induced hypoglycemia. If the needle is not kept straight while you attach it, it can damage the rubber seal and cause leakage, or break the needle. Insert the needle into rubber stopper of the NPH insulin vial and inject the air into the vial this will make the insulin easier to remove.


Moderate Monitor patients receiving monoamine oxidase inhibitors MAOIs concomitantly with insulin for changes in glycemic control. Elderly qpidra are at risk for hypoglycemia as well as those who have brittle diabetes, have received an overdose of insulin, have a delayed or decreased insrt intake, or undergo an excessive amount of exercise relative to their usual insulin dose.

Fast-Acting, Mealtime Insulin | Apidra® (insulin glulisine [rDNA origin] injection)

Packs of 1, 3, 4, 5, 6, 8, 9 and 10 prefilled pens are available. Hepatic disease, renal impairment, or renal failure may affect dosage requirements of insulin like insulin glulisine.

Always have a spare SoloStar in case your SoloStar is lost or damaged. This could lead to severe hyperglycaemia very high blood sugar and ketoacidosis build-up of acid in the blood because the body is breaking down fat instead of sugar. When insulin glulisine is administered as intermittent injections in patients with type 1 diabetes mellitus, or when used as monotherapy in patients with type 2 diabetes mellitus, a longer-acting insulin should be part of the therapeutic regimen to maintain adequate glucose control.

Dosage varies depending on previous regimen, concurrent medications, lifestyle, etc. Because hypoglycemic events may be difficult to recognize in some elderly patients, the initial dosing and dosing increments of any insulin product should be conservative. Keep the pre-filled pen in the outer carton in order to protect from light.

It is made by biotechnology.